Monday, November 3, 2008

Plavix


From Wikipedia

Clopidogrel is a potent oral antiplatelet agent often used in the treatment of coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade names Iscover and Plavix respectively, by Sun Pharmaceuticals under the trade name Clopilet and by Ranbaxy Laboratories under the trade name Ceruvin. It works by blocking a receptor called P2Y12. Adverse effects include hemorrhage.

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Adverse effects


Severe neutropenia (Incidence: 1/2,000)

Thrombotic thrombocytopenic purpura (TTP) (Incidence:
4/1,000,000 patients treated)

Hemorrhage - The incidence of hemorrhage may be
increased by the co-administration of aspirin.[4]

Gastrointestinal Hemorrhage (Incidence: 2.0%)

Cerebral Hemorrhage (Incidence: 0.1 to 0.4%)

Use of non-steroidal anti-inflammatory drugs is
discouraged inthose taking clopidogrel due to
increased risk of digestive tract hemorrhage


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Consumer comments

Ask-a-Patient: Rating: 2.6


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Official Site

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